A. V. Kustov, M. A. Krestyaninov, S. O. Kruchin, O. V. Shukhto, T. V. Kustova, D. V. Belykh, I. S. Khudyaeva, O. I. Koifman, P. B. Razgovorov, D. B. Berezin, “Interaction of cationic chlorin photosensitizers with non-ionic surfactant Tween 80”, Mendeleev Commun., 2021, Volume 31, Issue 1,Pages <nobr>65

This article is cited in 15 papers

Communications

Interaction of cationic chlorin photosensitizers with non-ionic surfactant Tween 80

A. V. Kustov^a, M. A. Krestyaninov^a, S. O. Kruchin^a, O. V. Shukhto^b, T. V. Kustova^b, D. V. Belykh^c, I. S. Khudyaeva^c, O. I. Koifman^b, P. B. Razgovorov^d, D. B. Berezin^b

^a G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russian Federation
^b Ivanovo State University of Chemistry and Technology, Ivanovo, Russian Federation
^c Institute of Chemistry, Komi Science Center, Ural Branch of the Russian Academy of Sciences, Syktyvkar, Russian Federation
^d Yaroslavl State Technical University, Yaroslavl, Russian Federation

Abstract: The interaction between cationic chlorophyll photosensitizers (PSs) for antimicrobial photodynamic therapy and non-ionic surfactant Tween 80 as a potential carrier system was studied using absorption and fluorescence spectroscopy. The results, analyzed in terms of our approach and the Stern–Volmer approach, indicate that all three PSs form stable molecular complexes with Tween 80, the PS molecules being located at the periphery of surfactant micelles next to hydrophilic head groups. The higher the charge of the macrocyclic cation, the stronger the interaction of PS with the surfactant.

Keywords: antimicrobial photodynamic therapy, photosensitizer, cationic chlorin, aggregation, non-ionic surfactant, Tween 80, binding constants, fluorescence quenching, carrier system.

Language: English

DOI: 10.1016/j.mencom.2021.01.019

	*Supplementary materials:*
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