K. V. Gulyás, G. T. Keglevich, “The surprising diacylation of diethyl (ethoxycarbonylmethyl)phosphonate”, Mendeleev Commun., 2021, Volume 31, Issue 2,Pages <nobr>244

This article is cited in 2 papers

Communications

The surprising diacylation of diethyl (ethoxycarbonylmethyl)phosphonate

K. V. Gulyás, G. T. Keglevich

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary

Abstract: Deprotonation of diethyl (ethoxycarbonylmethyl)-phosphonate with NaH followed by treatment with acyl chlorides affords surprisingly the corresponding C,C-diacylated derivatives as the predominating products.

Keywords: CH-acidic compounds, phosphonates, acylation, diacylation, relative DpKa value.

Language: English

DOI: 10.1016/j.mencom.2021.03.033

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