I. V. Galkina, D. I. Bakhtiyarov, L. M. Usupova, A. V. Gerasimov, M. P. Shulaeva, O. K. Pozdeev, A. V. Ilyasov, D. R. Islamov, K. S. Usachev, Yu. V. Bakhtiyarova, V. I. Galkin, “Antimicrobial activity of novel isothiuronium salts with 7-chloro-4,6-dinitrobenzofuroxan-5-olate anion”, Mendeleev Commun., 2021, Volume 31, Issue 3,Pages <nobr>365

This article is cited in 2 papers

Communications

Antimicrobial activity of novel isothiuronium salts with 7-chloro-4,6-dinitrobenzofuroxan-5-olate anion

I. V. Galkina^a, D. I. Bakhtiyarov^a, L. M. Usupova^b, A. V. Gerasimov^a, M. P. Shulaeva^c, O. K. Pozdeev^c, A. V. Ilyasov^d, D. R. Islamov^a, K. S. Usachev^e, Yu. V. Bakhtiyarova^a, V. I. Galkin^a

^a Alexander Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russian Federation
^b Kazan National Research Technological University, Kazan, Russian Federation
^c Kazan State Medical University, Kazan, Russian Federation
^d Tatarstan Academy of Sciences, Kazan, Russian Federation
^e A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation

Abstract: New thermally stable long-chained 2-alkylisothiuronium 7-chloro-4,6-dinitrobenzofuroxan-5-olates were obtained from the corresponding bromides and 5,7-dichloro-4,6-dinitrobenzofuroxan, the hydrolysis of the C(5)–Cl bond to produce phenolic function having occurred in the course of the process. The compound structure was determined by IR spectroscopy, elemental analysis and X-ray single crystal study. Salts with C₁₄–C₁₈ alkyl groups revealed moderate antibacterial and antifungal activities.

Keywords: benzofuroxan-5-olates, nitroarenes, isothiuronium salts, hydrolysis, antimicrobial activity, X-ray diffraction.

Language: English

DOI: 10.1016/j.mencom.2021.04.027

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