B. V. Paponov, D. A. Rakityansky, M. S. Samokhvalova, G. Denisov, A. Yu. Potapov, Kh. S. Shikhaliev, “Ring switching tricomponent synthesis of pyrano[2,3-<i>b</i>]pyridine multifunctional derivatives”, Mendeleev Commun., 2021, Volume 31, Issue 3,Pages <nobr>407

Communications

Ring switching tricomponent synthesis of pyrano[2,3-b]pyridine multifunctional derivatives

B. V. Paponov^a, D. A. Rakityansky^a, M. S. Samokhvalova^a, G. Denisov^b, A. Yu. Potapov^c, Kh. S. Shikhaliev^c

^a Belgorod State National Research University, Belgorod, Russian Federation
^b A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^c Voronezh State University, Voronezh, Russian Federation

Abstract: New 3-acylamino-7-hydroxy-5-methyl-2-oxo-2H-pyrano[2,3-b]pyridine-6-carbonitriles were synthesized via a tricomponent condensation of 3-cyano-4-methyl-1,2,5,6-tetrahydropyridine-2,6-dione, triethyl orthoformate and N-acylglycines under the Erlenmeyer–Plöchl reaction conditions. According to X-ray data, in the solid phase they exist as hydroxypyridine tautomer form.

Keywords: 2H-pyrano[2,3-b]pyridinones, 1,2,5,6-tetrahydropyridine-2,6-dione, hippuric acid, triethyl orthoformate, tricomponent condensation, ring switching, Erlenmeyer–Plöchl reaction.

Language: English

DOI: 10.1016/j.mencom.2021.04.041

	*Supplementary materials:*
		Supplementary_data_1.pdf	1.9 Mb