N. Ya. Spivak, N. D. Nosenko, N. M. Zholobak, A. B. Shcherbakov, A. G. Reznikov, O. S. Ivanova, V. K. Ivanov, Yu. D. Tret'yakov, “The nanocrystalline cerium dioxide raises the functional activity of genesial system of ageing males of rats”, Nanosystems: Physics, Chemistry, Mathematics, 2013, Volume 4, Issue 1,Pages <nobr>72

The nanocrystalline cerium dioxide raises the functional activity of genesial system of ageing males of rats

N. Ya. Spivak^ab, N. D. Nosenko^c, N. M. Zholobak^a, A. B. Shcherbakov^a, A. G. Reznikov^c, O. S. Ivanova^d, V. K. Ivanov^def, Yu. D. Tret'yakov^def

^a D.K. Zabolotny Institute of Microbiology and Virology of the NASU, Kiev, Ukraine
^b DiaProfMed LLC, Kiev, Ukraine
^c Institute of Endocrinology and Metabolism named after V.P. Komissarenko of the National Academy of Medical Sciences of Ukraine, Kiev, Ukraine
^d Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
^e Lomonosov Moscow State University, Faculty of Materials Science
^f Lomonosov Moscow State University, Faculty of Chemistry

Abstract: Effect of a nanocrystalline cerium dioxide (nanoceria) on the reproductive system of elderly male rats has been studied. It was shown that nanoceria administration (1 mg/kg for 10 days) considerably increases testosterone level, quantity of spermatozoa and quantity of rat cubs in the litter born by pubertal intact females. Physical and sexual development of rat cubs in the test group did not differ from the control.

Keywords: nanocrystalline cerium dioxide, male rats, testosterone, spermatozoa.

UDC: 546.655.4-31 + 599.323.41 : 591.139 : 591.463 : 612.063 : 4.09

PACS: 87.85.Rs