U. A. Malkova, E. V. Demidov, N. V. Kuzmina, A. Yu. Plekhanov, M. V. Puzyk, “Spectro-luminescent research of 1-pyrenemethylamine interaction with nucleic acids in water”, Optics and Spectroscopy, 2024, Volume 132, Issue 7,Pages <nobr>786–788</nobr>

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Optics and Spectroscopy, 2024 Volume 132, Issue 7, Pages 786–788 (Mi os1232)

Biophotonics

Spectro-luminescent research of 1-pyrenemethylamine interaction with nucleic acids in water

U. A. Malkova^a, E. V. Demidov^a, N. V. Kuzmina^b, A. Yu. Plekhanov^c, M. V. Puzyk^a

^a Herzen State Pedagogical University of Russia, St. Petersburg, Russia
^b Federal State Budgetary Educational Institution of Higher Education Saint Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation, St. Petersburg, Russia
^c Smorodintsev Research Institute of Influenza (a Russian Ministry of Health federal institution), St. Petersburg, Russia

Abstract: The interactions of 1-pyrenemethylamine hydrochloride with nucleic acids (calf thymus DNA and yeast RNA) in water were studied using electron absorption and emission spectroscopy. The totality of the obtained spectral data allows us to conclude that 1-pyrenemethylamine is intercalated in DNA but not in RNA.

Keywords: intercalation, 1-pyrenemethylamine, calf thymus DNA, yeast RNA.

Received: 12.07.2024
Revised: 26.07.2024
Accepted: 29.07.2024

DOI: 10.61011/OS.2024.07.58904.6892-24

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© Steklov Math. Inst. of RAS, 2025