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JOURNALS // Optics and Spectroscopy // Archive

Optics and Spectroscopy, 2023 Volume 131, Issue 1, Pages 116–122 (Mi os1279)

Biophotonics

Application of the method of absorption diode laser spectroscopy for measuring the content of $^{13}$Ñ and $^{12}$Ñ in exhaled air

S. V. Kireev, A. A. Kondrashov, S. L. Shnyrev

National Engineering Physics Institute "MEPhI", 115409 Moscow, Russia

Abstract: The paper reports on experimental studies of the absorption of $^{13}$Ñ$^{16}$Î$_2$ in a mixture with $^{12}$Ñ$^{16}$Î$_2$ in exhaled air by laser absorption spectroscopy using a diode laser tunable in the frequency range 4860–4880 cm$^{-1}$. The results of the studies showed that the minimum detectable concentration of $^{13}$Ñ$^{16}$Î$_2$ is at a level of less than 20 ppm, and this approach is promising for measuring the content of $^{13}$Ñ$^{16}$Î$_2$ in exhaled air for non-invasive online diagnosis of oncological diseases of the gastrointestinal tract at early stages.

Keywords: diode laser spectroscopy, carbon dioxide, breath tests, oncological diseases of the gastrointestinal tract.

Received: 07.06.2022
Revised: 05.11.2022
Accepted: 19.12.2022

DOI: 10.21883/OS.2023.01.54548.3776-22



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