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JOURNALS // Optics and Spectroscopy // Archive

Optics and Spectroscopy, 2020 Volume 128, Issue 7, Pages 1020–1029 (Mi os381)

This article is cited in 9 papers

UV, IR, and terahertz optics

Optical properties of hyperosmotic agents for immersion clearing of tissues in terahertz spectroscopy

G. R. Musinaab, A. A. Gavdushab, N. V. Chernomyrdinab, I. N. Dolganovabc, V. E. Ulitkoc, O. P. Cherkasovade, V. N. Kurlovc, G. A. Komandina, I. V. Zhivotovskiib, V. V. Tuchinefg, K. I. Zaitsevab

a Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow
b Bauman Moscow State Technical University
c Institute of Solid State Physics, Russian Academy of Sciences, Chernogolovka, Moscow region
d Institute of Laser Physics, Siberian Branch, Russian Academy of Sciences, Novosibirsk
e Tomsk State University
f Saratov State University
g Institute of Precision Mechanics and Control, Russian Academy of Sciences, Saratov

Abstract: We measured the transmission spectra of the most common hyperosmotic agents, such as pure glycerol, propylene glycol (PG), dimethyl sulfoxide (DMSO), polyethylene glycol (PEG) with molecular weights of 200, 300, 400, and 600 Da, their aqueous solutions, and aqueous solutions of sucrose, glucose, fructose, and dextran 40 and 70. The experiments were carried out using a THz pulsed spectrometer with an evacuated measuring compartment to eliminate the effect of water vapor on spectral measurements. We reconstructed the dielectric characteristics of hyperosmotic agents in the spectral range from 0.1 to 2.5 THz and plotted a dependence of the amplitude absorption coefficient on the concentration of the considered agents at a frequency of 0.5 THz. The results are useful for selecting optimal agents for immersion optical clearing in the THz range.

Keywords: terahertz technologies, terahertz pulsed spectroscopy, dielectric spectroscopy, immersion optical clearing, clearing agents, dehydrating agents.

Received: 18.02.2020
Revised: 03.03.2020
Accepted: 28.03.2020

DOI: 10.21883/OS.2020.07.49576.65-20


 English version:
Optics and Spectroscopy, 2020, 128:7, 1026–1035

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