K. I. Timoshchuk, M. M. Khalisov, V. A. Penniyaynen, B. V. Krylov, A. V. Ankudinov, “Probing mechanical characteristics of living fibroblasts via atomic force microscopy”, Pisma v Zhurnal Tekhnicheskoi Fiziki, 2019, Volume 45, Issue 18,Pages <nobr>44

This article is cited in 4 papers

Probing mechanical characteristics of living fibroblasts via atomic force microscopy

K. I. Timoshchuk^a, M. M. Khalisov^a, V. A. Penniyaynen^a, B. V. Krylov^a, A. V. Ankudinov^b

^a Pavlov Institute of Physiology Russian Academy of Sciences
^b Ioffe Institute, St. Petersburg

Abstract: Atomic force microscopy (AFM) measurements have revealed hardening of intact fibroblasts after treatment with colchicine. The reliability of AFM measurements was confirmed by the identification of cells the lateral response of which to indentation did not disturb the normal force contribution. AFM data on the mechanical characteristics of such cells admit an unambiguous interpretation.

Keywords: atomic force microscopy, fibroblasts, colchicine.

Received: 16.05.2019
Revised: 16.05.2019
Accepted: 13.06.2019

DOI: 10.21883/PJTF.2019.18.48238.17878