Three-dimensional simulation of flows in microchannels with deterministic lateral displacement system using the boundary element method

Microfluidic systems with deterministic lateral displacement (DLD) are one of the most effective technologies for particle control in the flow. In this paper, the influence of the geometry features of microchannels with DLD on the hydrodynamic features of fluid flows is investigated. Numerical modelling was performed for the three-dimensional case using the Boundary Element Method, accelerated by the Fast Multipole Method on heterogeneous computing architectures. The effect of the DLD structures shape and row displacement on the velocity distribution in the channel has been studied. Additionally, the variation of the velocity gradient between rows of structures and in the gaps between two neighbouring columns has also been examined.