Ya. V. Fattakhov, A. R. Fakhrutdinov, D. A. Konovalov, V. L. Odivanov, V. A. Shagalov, A. A. Bayazitov, F. V. Bashirov, V. A. Markosyan, V. M. Vodovozov, A. V. Pavlenko, R. F. Kurunov, V. M. Baev, M. V. Kuleshov, V. V. Eremkin, A. A. Baturina, M. S. Sirko, “Development of equipment and techniques for magnetic resonance imaging of laboratory animals' lungs using hyperpolarized <nobr>$^{129}$</nobr>Xe”, Pisma v Zhurnal Tekhnicheskoi Fiziki, 2025, Volume 51, Issue 22,Pages <nobr>49

Development of equipment and techniques for magnetic resonance imaging of laboratory animals' lungs using hyperpolarized $^{129}$Xe

Ya. V. Fattakhov^a, A. R. Fakhrutdinov^a, D. A. Konovalov^a, V. L. Odivanov^a, V. A. Shagalov^a, A. A. Bayazitov^a, F. V. Bashirov^b, V. A. Markosyan^b, V. M. Vodovozov^c, A. V. Pavlenko^c, R. F. Kurunov^c, V. M. Baev^c, M. V. Kuleshov^c, V. V. Eremkin^c, A. A. Baturina^c, M. S. Sirko^c

^a Zavoisky Physical Technical Institute, Kazan Scientific Center of the Russian Academy of Sciences
^b Kazan State Medical University
^c D. V. Efremov Scientific Research Institute of Electrophysical Apparatus, St. Petersburg

Abstract: A technique for obtaining NMR tomograms of laboratory animals' lungs using hyperpolarized (GP) $^{129}$Xe has been developed. A facility for producing GP $^{129}$Xe has been created, a magnetic resonance imaging machine has been adapted to work on xenon cores, and a device for controlling the respiration of laboratory animals has been developed and manufactured. The technology of tracheostomy of laboratory animals has been developed to ensure their respiration when receiving lung tomograms. An experiment was conducted to obtain lung tomograms of laboratory animals using GP $^{129}$Xe.

Keywords: magnetic resonance imaging, hyperpolarized $^{129}$Xe, artificial lung ventilation, laboratory animals.

Received: 29.05.2025
Revised: 11.08.2025
Accepted: 21.08.2025

DOI: 10.61011/PJTF.2025.22.61585.20392