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Pisma v Zhurnal Tekhnicheskoi Fiziki, 2026 Volume 52, Issue 4, Pages 16–19 (Mi pjtf9727)

Assessment of absorbed dose distribution for the in vitro setup at the VITA facility

D. S. Petrunyaab, M. Yu. Azarkina, I. N. Zavestovskayaab, D. A. Kasatovc, M. R. Kirakosyana, Ya. V. Razdrogovaa, S. Yu. Taskaevadc

a P. N. Lebedev Physical Institute, Russian Academy of Sciences, Moscow
b National Research Centre "Kurchatov Institute", Moscow
c G I. Budker Institute of Nuclear Physics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk
d Novosibirsk State University

Abstract: In this study, the spatial distribution of an absorbed dose and its components were assessed for the in vitro setup of the VITA accelerator-based neutron source, operating at the Budker Institute of Nuclear Physics, Siberian Branch of the Russian Academy of Sciences. Namely, the total and boron doses were obtained for cryovials placed at different distances from the neutron field axis. The cryovials contained a cell suspension doped with the realistic concentration of $^{10}$B isotope. Additionally, the dependence of the quantities on the neutron moderator chemical composition and thickness was investigated.

Keywords: boron neutron capture therapy, absorbed dose, in vitro setup, Monte Carlo simulation.

Received: 10.06.2025
Revised: 13.10.2025
Accepted: 13.10.2025

DOI: 10.61011/PJTF.2026.04.62319.20404



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© Steklov Math. Inst. of RAS, 2026