Effect of acoustic exposing on blood flow in microchannel simulating stenosis

The work is dedicated to problems connected with blood clot formation and study of blood flow features in vessels with stenosis. Using high-speed recording an analysis of flow structure of biological dispersion (blood) in acoustic field of mild intensity is made. It carried out in microchannel simulating a blood vessel with stenosis made and using soft lithography technology. The flow is arranged at constant pressure drop provided by hydrostatic pump in a range of 100–800 Pa. It was found a strong influence of acoustic field on a dynamics of blood flow in a microchannel at the range of frequencies 20–500 kHz and amplitudes below than 50 kPa. Results show reciprocating movements of flow in a region of microchannel narrowing. It is found a possibility of ultrasound field impact on blood clots formed in region of vessels stenosis.