A. M. Spitsina, Yu. L. Orlov, N. N. Podkolodnaya, A. V. Svichkarev, A. I. Dergilev, M. Chen, S. V. Kuchin, I. G. Chernykh, B. M. Glinskij, “Supercomputer analysis of genomics and transcriptomics data revealed by high-throughput DNA sequencing”, Program Systems: Theory and Applications, 2015, Volume 6, Issue 1,Pages <nobr>157

This article is cited in 3 papers

Hardware, software and distributed supercomputer systems

Supercomputer analysis of genomics and transcriptomics data revealed by high-throughput DNA sequencing

A. M. Spitsina^a, Yu. L. Orlov^a, N. N. Podkolodnaya^a, A. V. Svichkarev^b, A. I. Dergilev^b, M. Chen^c, S. V. Kuchin^d, I. G. Chernykh^d, B. M. Glinskij^d

^a Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences
^b Novosibirsk State University
^c Zhejiang University
^d Institute of Computational Mathematics and Mathematical Geophysics SB RAS

Abstract: Development of high-throughput DNA sequencing technologies lead to new classes of bulk genomic data and consequent development of specialized algorithms and software. Supercomputing is necessary tool to deal with modern genetics data. We present technical problems related to gene expression analysis, genomics and transcriptomics data, as well as sequencing technologies related to gene expression. Approaches for automatic genome data annotation are discussed. (In Russian).

Key words and phrases: bioinformatics, DNA sequencing, microarrays, gene expression regulation, transcription, databases.

UDC: 004.031.2

Received: 26.12.2014
Accepted: 24.02.2015