Abstract:
High-performance DNA sequencing technologies allow to obtain gene expression data in the genome scale from microchips and transcriptome profiling.
It is necessary to develop new computational methods, based on supercomputer technologies, to analyze such data.
The problems of gene expression analysis in the context of computational complexity are considered.
We present application examples of the multifunctional software package ExpGene for analysis and visualization of transcriptomics and microarray data.
We consider examples of analysis of laboratory animal brain areas gene expression data. (In Russian).
Key words and phrases:bioinformatics, program complex, DNA sequencing, transcriptome, gene expression, microarrays, databases.