A. A. Angeluts, A. B. Gapeyev, M. N. Esaulkov, O. G. Kosareva, S. N. Matyunin, M. M. Nazarov, T. N. Pashovkin, P. M. Solyankin, O. P. Cherkasova, A. P. Shkurinov, “Study of terahertz-radiation-induced DNA damage in human blood leukocytes”, Kvantovaya Elektronika, 2014, Volume 44, Number 3,Pages <nobr>247

This article is cited in 32 papers

Biophotonics

Study of terahertz-radiation-induced DNA damage in human blood leukocytes

A. A. Angeluts^ab, A. B. Gapeyev^c, M. N. Esaulkov^ab, O. G. Kosareva^ab, S. N. Matyunin^d, M. M. Nazarov^e, T. N. Pashovkin^c, P. M. Solyankin^ab, O. P. Cherkasova^f, A. P. Shkurinov^ab

^a Lomonosov Moscow State University, Faculty of Physics
^b International Laser Center of Moscow State University
^c Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moskovskaya obl.
^d Section of Applied Problems at the Presidium of the Russian Academy of Sciences, Moscow
^e Institute on Laser and Information Technologies, Russian Academy of Scienses, Shatura, Moscow Region
^f Institute of Laser Physics, Siberian Branch, Russian Academy of Sciences, Novosibirsk

Abstract: We have carried out the studies aimed at assessing the effect of terahertz radiation on DNA molecules in human blood leukocytes. Genotoxic testing of terahertz radiation was performed in three different oscillation regimes, the blood leukocytes from healthy donors being irradiated for 20 minutes with the mean intensity of 8 – 200 mW cm^-2 within the frequency range of 0.1 – 6.5 THz. Using the comet assay it is shown that in the selected regimes such radiation does not induce a direct DNA damage in viable human blood leukocytes.

Keywords: terahertz radiation, human blood leukocytes, genotoxic effect, comet assay, safety levels.

PACS: 42.62.Be, 87.50.W-, 87.14.gk

Received: 29.10.2013