E. S. Tuchina, P. O. Petrov, K. V. Kozina, F. Ratto, S. Centi, R. Pini, V. V. Tuchin, “Using gold nanorods labelled with antibodies under the photothermal action of NIR laser radiation on $\it{Staphylococcus}$ $\it{aureus}$”, Kvantovaya Elektronika, 2014, Volume 44, Number 7,Pages <nobr>683

This article is cited in 15 papers

Laser biophotonics

Using gold nanorods labelled with antibodies under the photothermal action of NIR laser radiation on $\it{Staphylococcus}$ $\it{aureus}$

E. S. Tuchina^a, P. O. Petrov^a, K. V. Kozina^a, F. Ratto^b, S. Centi^c, R. Pini^b, V. V. Tuchin^ade

^a Saratov State University named after N. G. Chernyshevsky
^b Italian National Research Council, Institute of Applied Physics, Sesto Fiorentino, Italy
^c University of Florence, Dept. Experimental and Clinical Biomedical Sciences, Firenze, Italy
^d Institute of Precision Mechanics and Control, Russian Academy of Sciences, Saratov
^e University of Oulu

Abstract: The effect of NIR laser radiation (808 nm) and gold nanorods on the cells of two strains of $\it{Staphylococcus}$ $\it{aureus}$, one of them being methicillin-sensitive and the other being methicillinresistant, is studied. Nanorods having the dimensions 10 × 44 nm with the absorption maximum in the NIR spectral region, functionalised with human immunoglobulins IgA and IgG, are synthesised. It is shown that the use of nanoparticles in combination with NIR irradiation leads to killing up to 97% of the population of microorganisms.

Keywords: NIR lasers, nanoparticles, antibodies, staphylococci.

PACS: 78.67.Qa, 87.50.wp, 87.19.xb

Received: 22.03.2014
Revised: 17.05.2014