Abstract:
We describe a Monte Carlo algorithm for simulating an interference signal and constructing a structural image of a biological object using optical coherent tomography (OCT). The algorithm is specific in that the object geometry is described by using a three-dimensional array of voxels combined into parallelograms, and the border cross checking is carried out by using an improved Smith algorithm. The geometry of the simulated object is reconstructed based on the structure of real biological tissues obtained by OCT. The algorithm efficiency is estimated by comparing experimental and corresponding simulated images of a subcutaneous blood vessel and upper layer of human skin in vivo.
Keywords:optical coherent tomography, coherent probing depth, blood vessels, Monte Carlo modelling, voxel-based model.