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Kvantovaya Elektronika, 2002 Volume 32, Number 11, Pages 945–952 (Mi qe2326)

This article is cited in 19 papers

Laser biology and medicine

Light scattering study of rheumatoid arthritis

J. Beuthana, U. Netza, O. Mineta, A. D. Kloseb, A. H. Hielscherb, A. Scheelc, J. Hennigerd, G. Müllera

a Institute for Medical Physics and Laser Medicine, Freie University of Berlin, Germany
b Columbia University, USA
c Department of Medicine, Nephrology and Rheumatology, Georg-August-University, Germany
d Department of Physics, Technical University Dresden, Germany

Abstract: The distribution of light scattered by finger joints is studied in the near-IR region. It is shown that variations in the optical parameters of the tissue (scattering coefficient μs, absorption coefficient μa, and anisotropy factor g) depend on the presence of the rheumatoid arthritis (RA). At the first stage, the distribution of scattered light was measured in diaphanoscopic experiments. The convolution of a Gaussian error function with the scattering phase function proved to be a good approximation of the data obtained. Then, a new method was developed for the reconstruction of distribution of optical parameters in the finger cross section. Model tests of the quality of this reconstruction method show good results.

PACS: 87.64.Dz, 87.53.Wz, 42.62.Be

Received: 12.09.2002


 English version:
Quantum Electronics, 2002, 32:11, 945–952

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