Macrokinetic aspects of the biocompatibility and biodegradation of polymers

We review the quantitative relationships between the degradation kinetics of the main classes of polymers (polyolefins, polyesters, polyamides, elastomers) used as implants. Their biocompatibility criteria and the reactions of the organism on the implants are considered, and the catalytic activity of biological media (water, salts, enzymes) are discussed together with problems in the metabolism and conjugation of the degradation products. The bibliography includes 127 references.