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Usp. Khim., 1979 Volume 48, Issue 5, Pages 957–973 (Mi rcr3138)

The Use of High-pressure Liquid Chromatography in the Analysis of the Structural Components of Nucleic Acids

V. K. Kagramanova, S. N. Bubenshchikova, L. A. Baratova

Lomonosov Moscow State University, Interfaculty Laboratory of Bioorganic Chemistry

Abstract: The advances in the analysis of the structural components of nucleic acids by high-pressure liquid chromatography are described and surveyed. The general ideas concerning the requirements imposed on sorbents at the present time in order to increase the efficiency of the chromatographic process are summarised. The methods and the results of the employment of effective ion-exchange sorbents in the separation and ultramicroanalysis of mixtures of the heterocyclic bases, nucleosides, nucleotides, and their derivatives are briefly considered.
The bibliography includes 82 references.

UDC: 547.962.32:543.544.45

DOI: 10.1070/RC1979v048n05ABEH002343


 English version:
Russian Chemical Reviews, 1979, 48:5, 517–526

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