Polyalkoxyflavonoids as inhibitors of cell division

Being structural analogues of natural microtubule-destabilizing cytostatics, polyalkoxyflavonoids represent a promising class of compounds for anticancer drug design. The review covers synthetic routes to various polyalkoxyflavonoids and the results of biological assays in vitro on human cancer cells and \it{in vivo} using sea urchin embryos as a model. Mechanisms of action and structure–relationship activity for polyalkoxyflavonoids are discussed.
The bibliography includes 151 references.