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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 2016 Volume 85, Issue 3, Pages 308–334 (Mi rcr4100)

This article is cited in 5 papers

Methods for the synthesis of aza(deaza)xanthines as a basis of biologically active compounds

D. A. Babkova, A. N. Geismana, A. L. Khandazhinskayab, M. S. Novikova

a Volgograd State Medical University
b Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Abstract: The review covers methods for the synthesis of aza(deaza)xanthines, i.e., fused pyrrolo-, pyrazolo- and triazolopyrimidine heterocyclic systems, which are common core structures of various biologically active compounds. The extensive range of modern synthetic approaches is organized according to target structures and starting building blocks. The presented material is intended to benefit broad audience of specialists in the fields of organic, medicinal and pharmaceutical chemistry.
The bibliography includes 195 references.

Received: 26.09.2014

DOI: 10.1070/RCR4496


 English version:
Russian Chemical Reviews, 2016, 85:3, 308–334

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