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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 2016 Volume 85, Issue 12, Pages 1277–1296 (Mi rcr4141)

This article is cited in 25 papers

Upconversion nanoparticles and their hybrid assemblies for biomedical applications

E. A. Grebenika, A. B. Kostyukb, S. M. Deyevcd

a Institute for Regenerative Medicine, I. M. Sechenov First Moscow State Medical University
b Institute of Biology and Biomedicine, National Research Lobachevsky State University of Nizhni Novgorod
c Tomsk Polytechnic University
d M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow

Abstract: The progress in the design of hybrid photoluminescent assemblies based on upconversion nanoparticles (UCNPs) meant for biomedical applications is analyzed. The key approaches to the synthesis of bright UCNPs and their surface modification, including encapsulation into hydrophilic shells and providing with therapeutic and targeting agents, are described. The range of potential applications of UCNPs in analytical biochemistry, biomedical diagnostics and therapy of cancer and infectious diseases is considered.
The bibliography includes 145 references.

Received: 04.05.2016

DOI: 10.1070/RCR4663


 English version:
Russian Chemical Reviews, 2016, 85:12, 1277–1296

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