Tetrazoles for biomedicine

The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents. This review summarizes data on the use of tetrazoles in biomedicine published in the last 10–15 years and also views on the nature of their biological effects. The prospects for the development of new biologically active substances containing a tetrazolyl pharmacophore are analyzed.
The bibliography includes 263 references.