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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 2011 Volume 80, Issue 2, Pages 182–198 (Mi rcr43)

This article is cited in 17 papers

Exogenous nitric oxide donors in the series of C-nitro compounds

V. G. Granik, N. B. Grigoriev

Centre for Medicinal Chemistry, All-Russian Research Chemical-Pharmaceutical Institute, Moscow

Abstract: The published data on nitrogen(II) oxide donors related to C-nitro compounds are generalized and described systematically. The key classes of these compounds and the possible mechanisms of their transformations under hydrolytic conditions and in living organisms are considered. The attention is focused on C-nitro compounds as potential medicinal agents for treating a broad range of diseases (cardiovascular diseases, tuberculosis, cancer, etc.).

Received: 13.01.2010

DOI: 10.1070/RC2011v080n02ABEH004135


 English version:
Russian Chemical Reviews, 2011, 80:2, 171–186

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