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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 2021 Volume 90, Issue 4, Pages 488–510 (Mi rcr4341)

This article is cited in 52 papers

Mono- and sesquiterpenes as a starting platform for the development of antiviral drugs

O. I. Yarovaya, N. F. Salakhutdinov

N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistryof the Siberian Branch of Russian Academy of Sciences

Abstract: The revies focuses on low-molecular-weight plant metabolites (mono- and sesquiterpenes) exhibiting antiviral activity. Data on antiviral action of both essential oils and plant extracts and their components are provided. Structures of biologically active natural mono- and sesquiterpenoids as well as their derivatives showing a pronounced antiviral activity are presented. A special attention is given to the description of targets for antiviral therapy. The mechanisms of action of antiviral agents are considered.
The bibliography includes 163 references.

Keywords: Viruses, monoterpene, sesquiterpene, antiviral mechanism.

Received: 15.06.2020

DOI: 10.1070/RCR4969


 English version:
Russian Chemical Reviews, 2021, 90:4, 488–510

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© Steklov Math. Inst. of RAS, 2025