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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 2023 Volume 92, Issue 1, Pages 1–27 (Mi rcr4411)

This article is cited in 7 papers

Antiviral properties of diterpenes and their derivatives

O. I. Yarovaya, S. S. Laev, N. F. Salakhutdinov

N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation

Abstract: The review focuses on low-molecular-weight natural metabolites of the diterpene series and their semi-synthetic analogues, which exhibit antiviral activity. Data on the antiviral activity of both plant extracts and their components are provided. The structures of biologically active natural diterpenoids and their derivatives with a pronounced antiviral effect are presented. Mechanisms of therapeutic action of diterpenoids and their derivatives with a pronounced antiviral effect are considered for different viruses. The review summarizes the data over the last 12 years (2011–2022).
The bibliography includes 183 references.

Keywords: Diterpene, Viruses, Antiviral mechanism.

Received: 13.06.2022

DOI: 10.57634/RCR5056


 English version:
Russian Chemical Reviews, 2023, 92:1, 1–26

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© Steklov Math. Inst. of RAS, 2025