D. V. Spector, D. S. Abramchuk, V. V. Bykusov, A. O. Zharova, E. S. Egorova, A. S. Voskresenskaya, A. R. Olovyanishnikov, I. A. Kuzmichev, A. A. Bubley, R. L. Antipin, E. K. Beloglazkina, O. O. Krasnovskaya, “BODIPY: synthesis, modification, and applications in sensing and biomedicine”, Usp. Khim., 2024, Volume 93, Issue 10,Pages <nobr>1

This article is cited in 1 paper

BODIPY: synthesis, modification, and applications in sensing and biomedicine

D. V. Spector^a, D. S. Abramchuk^a, V. V. Bykusov^a, A. O. Zharova^a, E. S. Egorova^a, A. S. Voskresenskaya^a, A. R. Olovyanishnikov^a, I. A. Kuzmichev^b, A. A. Bubley^a, R. L. Antipin^a, E. K. Beloglazkina^a, O. O. Krasnovskaya^a

^a Chemistry Faculty, Lomonosov Moscow State University, Moscow, Russian Federation
^b V.P.Serbsky National Medical Research Center for Psychiatry and Narcology, Moscow, Russian federation

Abstract: BODIPY chromophores (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) are one of the most versatile fluorophores which are commonly used in a variety of scientific fields. The combination of excellent photophysical properties with the possibility of easy chemical modification of structure, chemical and photostability determines the application of BODIPY in biomedicine, photocatalysis, analytical chemistry and materials science. This review summarizes approaches to the synthesis and modification of BODIPY, discussing both classical and recently-published synthetic and postfunctionalization approaches. An influence of BODIPY structure and various postfunctionalization methods on photophysical properties of the fluorophores and their potential applications in biomedicine, materials science and biosensorics are also discussed.
The bibliography includes 344 references.

Keywords: Boron-dipyrromethenes, BODIPY, postmodification, photodynamic therapy, photothermal therapy, fluorescent probes, photocatalysis, J-aggregates.

Received: 04.06.2024

DOI: 10.59761/RCR5136