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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 2013 Volume 82, Issue 9, Pages 896–915 (Mi rcr667)

This article is cited in 25 papers

New inhibitors of Mycobacterium tuberculosis growth based on modified pyrimidine nucleosides and their analogues

E. R. Shmalenyuk, S. N. Kochetkov, L. A. Alexandrova

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Abstract: Data on the methods of synthesis and antituberculosis activities of pyrimidine nucleoside derivatives and their analogues are summarized. A number of enzymes, promising targets for the prototypes of a new generation of drugs, are considered. The nucleosides able to inhibit drug-resistant strains of M. tuberculosis are characterized.
The bibliography includes 102 references.

Received: 26.04.2013

DOI: 10.1070/RC2013v082n09ABEH004404


 English version:
Russian Chemical Reviews, 2013, 82:9, 896–915

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