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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 1991 Volume 60, Issue 4, Pages 852–880 (Mi rcr925)

This article is cited in 5 papers

Synthesis and reactivity of $\mathrm{N}$-substituted aminoamides, antiarrhythmic and local anaesthetic activity

G. A. Tolstikova, E. Ya. Borisovab, M. I. Cherkashinc, V. M. Komarovb, E. V. Arzamastsevb

a Institute of Chemistry of the Bashkir Scientific Center, Ural Branch of the USSR, Ufa
b M. V. Lomonosov Moscow Institute of Fine Chemical Technology
c Institute of Chemical Physics of the USSR Academy of Sciences, Moscow

Abstract: Preparative methods, reactivity and biological action of $\mathrm{N}$-substituted aminoamides of the monoacylated diamine type $\mathrm{RCONH}-\overset{|}{\underset{|}{\mathrm{C}}}-(\mathrm{CH}_2)_n\mathrm{N}\!\!<$ are considered and systematised. An interconnection has been shown between structure, reactivity and the pharmacological activity of aminoamides. The bibliography contains 201 references.

UDC: 547.298.1, 547.554

DOI: 10.1070/RC1991v060n04ABEH001087


 English version:
Russian Chemical Reviews, 1991, 60:4, 420–434

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