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JOURNALS // Sibirskii Zhurnal Industrial'noi Matematiki // Archive

Sib. Zh. Ind. Mat., 2020 Volume 23, Number 4, Pages 30–47 (Mi sjim1107)

This article is cited in 3 papers

Mathematical model of the aseptic inflammation dynamics

O. F. Voropaevaa, T. V. Bayadilovba

a Federal Research Center for Information and Computational Technologies, pr. Acad. Lavrentyeva 6, Novosibirsk 630090, Russia
b Novosibirsk State University, ul. Pirogova 1, Novosibirsk 630090, Russia

Abstract: We present a new mathematical model of the aseptic inflammation dynamics. The adequacy of the model is confirmed by a qualitative and quantitative agreement with the laboratory data on the dynamics of the inflammatory process factors in the central zone of wound damage. We show that the model adequately describes not only the classical version of this process but also the available scenarios of acute and chronic inflammatory processes in aseptic cutaneous wound accompanied by the most common dysfunctions of blood cells or its cellular composition.

Keywords: aseptic inflammation, excision wound, mathematical model, sensitivity, leukocyte, cytokine, efferocytosis, thrombocythemia, thrombocytopenia, leukopenia, aplastic anemia. .

UDC: 519.6:51.76

Received: 13.04.2020
Revised: 09.07.2020
Accepted: 10.09.2020

DOI: 10.33048/SIBJIM.2020.23.403


 English version:
Journal of Applied and Industrial Mathematics, 2020, 14:4, 779–791

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