I. I. Chernyavsky, T. Alexandrov, S. I. Nikolenko, “Segmentation of MALDI imaging results based on graphical models”, Tr. SPIIRAN, 2012, Issue 21,Pages <nobr>120

Segmentation of MALDI imaging results based on graphical models

I. I. Chernyavsky^a, T. Alexandrov, S. I. Nikolenko^ab

^a St. Petersburg Department of V. A. Steklov Institute of Mathematics, Russian Academy of Sciences
^b St. Petersburg Academic University — Nanotechnology Research and Education Centre of the Russian Academy of Sciences (the Academic University)

Abstract: We consider the MALDI imaging segmentation problem and propose an approach based on graphical models (LDA model and Markov random fields). We consider several modifications to the proposed approach and compare it to the previously known methods; we distinguish several advantages of the proposed approach.

Keywords: MALDI, mass spectrometry, segmentation, graphical model, LDA, Markov random field, Ising model.

UDC: 004.8

Received: 07.06.2012