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JOURNALS // Informatics and Automation // Archive

Tr. SPIIRAN, 2002 Issue 1, volume 1, Pages 240–257 (Mi trspy83)

Information Mechanisms of Neuron and Neural memory

A.N. Radchenko


Abstract: The scheme of biophysical processes of neuron and neural memory based on conformational changes of soma-dendrite membrane is investigated. It is shown, that the "spontaneous" activity, produced by these changes in neuron membrane is determined in reality by afferent signals, as well as both combinatorial and geometrical specificity of synaptic environment of conformation clusters. The array of such clusters and their responses to chemical and electrical stimulations is analyzed. The relationship is found between biomolecular and neurophysiologic phenomena, including correspondence between three conformation states of receptive clusters and gating charge function, that defines closed, open and inactivated state of ion channels,. The inactivation is connected with engram forming. The selective properties of conformation clusters are described with an information model, which allows deriving information-transforming function of the neuron.

UDC: 612.821.2



© Steklov Math. Inst. of RAS, 2024