Abstract:
One of the simplest molecular motors, a biological microtubule, is reviewed as an example of a highly nonequilibrium molecular machine capable of stochastic transitions between slow growth and rapid disassembly phases. Basic properties of microtubules are described, and various approaches to simulating their dynamics, from statistical chemical kinetics models to molecular dynamics models using the Metropolis Monte Carlo and Brownian dynamics methods, are outlined.
PACS:87.10.-e, 87.16.-b, 87.16.A-
Received:March 14, 2016 Revised:April 4, 2016 Accepted: April 12, 2016