V. M. Aslanian, Y. B. Dalyan, S. G. Haroutiunian, “Структурные особенности ДНК в щелочной среде”, Proceedings of the YSU, Physical and Mathematical Sciences, 1987, Issue 2,Pages <nobr>80

Physics

Структурные особенности ДНК в щелочной среде

V. M. Aslanian^a, Y. B. Dalyan^a, S. G. Haroutiunian^a

^a Yerevan State University

Abstract: A specific mechanism of deprotonization of DNA nitrogen bases in alkaline media (pH>7.0) has been suggested. It has been shown that at pH>10.3 deprotonization of nitrogen bases in GC-rich helical regions can take place. It has been estimated that the character of DNA helix-coil transition temperature and interval dependences on pH is due to deprotonization selectivity of nitrogen bases only.

UDC: 577.3:547.963.3

Received: 12.02.1987
Accepted: 19.05.1987