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JOURNALS // Uchenye Zapiski Kazanskogo Universiteta. Seriya Fiziko-Matematicheskie Nauki // Archive

Uchenye Zapiski Kazanskogo Universiteta. Seriya Fiziko-Matematicheskie Nauki, 2018 Volume 160, Book 1, Pages 51–60 (Mi uzku1430)

This article is cited in 1 paper

Modification of the laser correlation spectrometer for analysis of biological fluids

E. N. Velichko, E. K. Nepomnyashchaya, E. T. Aksenov

Peter the Great St. Petersburg Polytechnic University, St. Petersburg, 195251 Russia

Abstract: Modifications of the laser correlation spectrometer system developed for the analysis of biological fluids have been discussed. Parameters of the proposed laser correlation spectrometer allowing to determine the sizes of nanoparticles in biological fluids, which are highly polydisperse solutions, to within 0.5 nm have been presented. We have explained the use of optical fiber in the spectrometer circuit as a system for collecting scattered radiation. Furthermore, we calculated the parameters of the discretization of the registered signals. It is for the correct selection of the ADC-converter. The results of the experiment showing significant differences in the size composition of donor blood serum proteins have been presented. Thus, the possibility for analyzing the composition of the blood serum of various donors and for obtaining diagnostic data has been proved.

Keywords: laser correlation spectroscopy, immune system, molecular analysis, blood serum.

UDC: 535.36+57.083.3+57.088.55

Received: 24.11.2017



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