E. V. Pisareva, A. B. Sokolovskaya, M. Y. Vlasov, “Modelling of steroidindused osteoresorption in the experiment during introduction of allogenic hydroxyapatite”, Vestnik Samarskogo Gosudarstvennogo Universiteta. Estestvenno-Nauchnaya Seriya, 2012, Issue 3/2(94),Pages <nobr>37

Biology

Modelling of steroidindused osteoresorption in the experiment during introduction of allogenic hydroxyapatite

E. V. Pisareva^a, A. B. Sokolovskaya^a, M. Y. Vlasov^b

^a Samara State University, Samara, 443011, Russian Federation
^b Institute of Experimental Medicine and Biotechnologies, Samara State Medicine University, Samara, 443079, Russian Federation

Abstract: The main spectrum of biochemical indices of blood serum in rats was investigated during steroid-induced osteoresorption. We have found the changes of bone metabolism markers under the influence of glucocortiсoids. It is established that the introduction of allogenic hydroxyapatite decrease the influence of glucocortiсoids on bone tissue.

Keywords: osteoresorption, glucocorticoids, hydroxyapatite.

UDC: 577.1