RUS  ENG
Full version
JOURNALS // Vestnik Samarskogo Universiteta. Estestvenno-Nauchnaya Seriya // Archive

Vestnik Samarskogo Gosudarstvennogo Universiteta. Estestvenno-Nauchnaya Seriya, 2015 Issue 3(125), Pages 164–173 (Mi vsgu475)

Chemistry

Analysis of multicomponent mixture on the example of the drug "Pentalgin” by the methods of TLC and IR-Fourier spectrometry

A. L. Lobachev, N. A. Red'kin, Yu. V. Trifonova

Samara State University, 1, Acad. Pavlov Str., Samara, 443011, Russian Federation

Abstract: The definition of a qualitative composition of multicomponent drugs "Pentalgin” and "Pentalgin ICN” by TLC and IR-spectrometry is carried out. It is shown that using just TLC or just FT-IR spectrometry does not allow us to identify all the major components. It has been proposed an authentication scheme, which includes the steps of isolating of the test components, their separation by TLC, followed by extraction of components and definition by FTIR spectrometry. The combination of these two techniques allows to separate and identify almost all the most important components of the mixture.

Keywords: FT-IR spectrometry, TLC, combination of methods, pentalgin, identification scheme, qualitative analysis, medicines, tablets, paracetamol, metamezol sodium, hydrochloride drotaverine.

UDC: 544.08, 544.355-16

Received: 25.12.2014



Bibliographic databases:


© Steklov Math. Inst. of RAS, 2024