Keywords: spermine-N-1-acetyltransferase; inhibitors; O-substituted hydroxylamines; polyamine analogues; fluoroquinolones; levofloxacin; derivatives; bacterial DNA gyrase; enzymatic activity; inhibition; amino acids; phosphorus analogues; glutamic acid; gamma-aminobutyric acid (GABA);targeting polyamine metabolism; initiation-factor; analogs; spermidine; growth; cancer; derivatives; inhibitors; therapy; enzymes

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• Engelhardt Institute of Molecular Biology, Russian Academy of Sciences