I. A. Doroshenko, K. G. Aminulla, V. N. Azev, T. M. Kulinich, V. A. Vasilichin, A. A. Shtil, T. A. Podrugina, “Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents”, Mendeleev Commun., 31:5 (2021), 615

Эта публикация цитируется в 8 статьях

Communications

Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents

I. A. Doroshenko^a, K. G. Aminulla^a, V. N. Azev^b, T. M. Kulinich^c, V. A. Vasilichin^a, A. A. Shtil^ad, T. A. Podrugina^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Branch of M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
^c Russian Scientific Center of Roentgenoradiology, Moscow, Russian Federation
^d N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation

Аннотация: New β-alanine modified tricarbocyanines containing various substituents at quaternized nitrogen atoms were obtained. The peptide synthesis method has been utilized for further conjugation thus giving promising tricarbocyanines containing two sulfonate groups and total negative charge of the fluorophore.

Ключевые слова: fluorophores, conjugates, β-alanine, cell-penetrating peptides, tricarbocyanine dyes, Fluorescent markers.

Язык публикации: английский

DOI: 10.1016/j.mencom.2021.09.008

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