D. O. Shkil, E. Yu. Yamansarov, B. N. Tarasevich, S. V. Kovalev, O. N. Metelkina, E. T. Yamansarova, N. V. Zyk, E. K. Beloglazkina, A. G. Majouga, “Mild and efficient catalyst for nitrodopamine synthesis: from milligram to multi-gram scales”, Mendeleev Commun., 34:2 (2024), 268

Communications

Mild and efficient catalyst for nitrodopamine synthesis: from milligram to multi-gram scales

D. O. Shkil^a, E. Yu. Yamansarov^ab, B. N. Tarasevich^a, S. V. Kovalev^a, O. N. Metelkina^a, E. T. Yamansarova^c, N. V. Zyk^a, E. K. Beloglazkina^a, A. G. Majouga^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Ufa State Petroleum Technoligical University, Ufa, Russian Federation
^c Ufa University of Science and Technology, Ufa, Russian Federation

Аннотация: Sodium hydrogen sulfate is proposed as a mild acidic catalyst for the dopamine nitration with sodium nitrite. This reagent system gives nitrodopamine in high yield and excellent purity and is suitable for routine synthesis from milligram to multi-gram scale.

Ключевые слова: dopamine, nitration, sodium nitrite, acid catalysis, nitrodopamine.

Язык публикации: английский

DOI: 10.1016/j.mencom.2024.02.034

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