I. G. Mamedov, F. N. Naghiev, A. M. Maharramov, O. Uwangue, A. Farewell, P. Sunnerhagen, M. Erdelyi, “Antibacterial activity of 2-amino-3-cyanopyridine derivatives”, Mendeleev Commun., 30:4 (2020), 498

Эта публикация цитируется в 20 статьях

Communications

Antibacterial activity of 2-amino-3-cyanopyridine derivatives

I. G. Mamedov^a, F. N. Naghiev^a, A. M. Maharramov^a, O. Uwangue^b, A. Farewell^b, P. Sunnerhagen^b, M. Erdelyi^c

^a Department of Chemistry, Baku State University, Baku, Azerbaijan
^b Department of Chemistry and Molecular Biology and the Center for Antibiotic Resistance Research (CARe), University of Gothenburg, Gothenburg, Sweden
^c Department of Chemistry, Uppsala University, Uppsala, Sweden

Аннотация: New 2-amino-4-aryl-3-cyanopyridines were obtained by the three-component condensation of arylidenemalononitriles, malononitrile and (di)amine system or acetoacetanilide. Antibacterial activity of all synthesized compounds against the Gram-negative bacteria E. coli and the Gram-positive B. subtilis was tested, the only representative showed a substantial antimicrobial effect.

Ключевые слова: 3,5-dicyanopyridines, antimicrobial activity, halogen bonding, bacteria, E. coli, B. subtilis.

Язык публикации: английский

DOI: 10.1016/j.mencom.2020.07.031

	*Дополнительные материалы:*
		Supplementary_data_1.pdf	2.8 Mb