A. S. Morkovnik, A. A. Zubenko, L. N. Divaeva, V. G. Kartsev, G. S. Borodkin, A. I. Klimenko, “The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines”, Mendeleev Commun., 29:1 (2019), 116

Эта публикация цитируется в 2 статьях

Communications

The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines

A. S. Morkovnik^a, A. A. Zubenko^b, L. N. Divaeva^a, V. G. Kartsev^c, G. S. Borodkin^a, A. I. Klimenko^d

^a Institute of Physical and Organic Chemistry, Southern Federal University, Rostov-on-Don, Russian Federation
^b North-Caucasian Zonal Research Veterinary Institute, Novocherkassk, Russian Federation
^c 'InterBioScreen Ltd.', Chernogolovka, Moscow Region, Russian Federation
^d Don State Agrarian University, Novocherkassk, Russian Federation

Аннотация: A simple method for pyridoxal structural modification via furan ring closure was developed resulting in 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines. The reaction products can be proposed as pyridoxal mimetics to inhibit pyridoxal 5′-phosphate-dependent enzymes.

Язык публикации: английский

DOI: 10.1016/j.mencom.2019.01.040

	*Дополнительные материалы:*
		Supplementary_data_1.pdf	496.2 Kb