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ЖУРНАЛЫ // Mendeleev Communications // Архив

Mendeleev Commun., 2019, том 29, выпуск 5, страницы 578–580 (Mi mendc1597)

Эта публикация цитируется в 2 статьях

Communications

Synthesis of blood group Forssman pentasaccharide GalNAcα1-3GalNAcβ1-3Galα1-4Galβ1-4Glcβ–R

I. S. Popovaa, E. Yu. Korchaginaa, M. A. Sablinaa, A. S. Paramonova, A. K. Hultb, S. M. Henryc, N. V. Bovinac

a M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
b Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden
c School of Engineering, Computer & Mathematical Sciences, Auckland University of Technology, Auckland, New Zealand


Аннотация: Synthesis of the glycan part of Forssman glycolipid GalNAcα1-3GalNAcβ1-3Galα1-4Galβ1-4Glc–Cer in the form of 2-aminoethyl glycoside has been carried out. The glycoside has been converted into a lipophilic derivative capable of controlled inserting into erythrocytes. The obtained surface-modified cells, termed kodecytes, revealed a high level of the blood group system FORS serological activity.

Язык публикации: английский

DOI: 10.1016/j.mencom.2019.09.034



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