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ЖУРНАЛЫ // Mendeleev Communications // Архив

Mendeleev Commun., 2019, том 29, выпуск 6, страницы 597–612 (Mi mendc1604)

Эта публикация цитируется в 8 статьях

Focus Article

Synthesis of glycans functioning as antigens of the ABO blood group system

I. M. Ryzhov, N. V. Bovin

M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation


Аннотация: Since the discovery of carbohydrate nature of the antigens related to ABO blood group system in the middle of 20th century, an interest to synthetic approaches to these oligosaccharides is very high. ABH glycans are required for clinical applications, namely, immunoadsorption and blood typing, as well as for scientific investigations in the areas of hematology, immunology and glycobiology. In this article, the chemical syntheses of various ABH glycans and related structures are reviewed, and examples of their use for clinical purposes are collected.

Язык публикации: английский

DOI: 10.1016/j.mencom.2019.11.001



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