A. M. Demin, T. R. Nizamov, A. G. Pershina, A. V. Mekhaev, M. A. Uimin, A. S. Minin, A. A. Zakharova, V. P. Krasnov, M. A. Abakumov, D. G. Zhukov, A. G. Savchenko, I. V. Schetinin, A. G. Majouga, “Immobilization of a pH-low insertion peptide onto SiO2/aminosilane-coated magnetite nanoparticles”, Mendeleev Commun., 29:6 (2019), 631

Эта публикация цитируется в 13 статьях

Communications

Immobilization of a pH-low insertion peptide onto SiO₂/aminosilane-coated magnetite nanoparticles

A. M. Demin^a, T. R. Nizamov^b, A. G. Pershina^cd, A. V. Mekhaev^a, M. A. Uimin^e, A. S. Minin^e, A. A. Zakharova^d, V. P. Krasnov^a, M. A. Abakumov^bf, D. G. Zhukov^b, A. G. Savchenko^b, I. V. Schetinin^b, A. G. Majouga^bf

^a I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^b National University of Science and Technology 'MISIS', Moscow, Russian Federation
^c Siberian State Medical University, Tomsk, Russian Federation
^d National Research Tomsk Polytechnic University, Tomsk, Russian Federation
^e M.N. Mikheev Institute of Metal Physics, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^f Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Аннотация: The covalent immobilization of a pH-low insertion peptide to aminosilane-coated magnetic nanoparticles with two core diameters (10 and 20nm) was carried out. The materials obtained were characterized by TEM, XRD, vibrating sample magnetometry, DLS, IR spectroscopy, TGA and elemental analyses. The materials did not have significant cytotoxicity, and they can be used as MRI-guided nanocarriers for tumour targeting.

Язык публикации: английский

DOI: 10.1016/j.mencom.2019.11.008

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