A. P. Dovzhenko, A. A. Betina, T. S. Bulatova, N. A. Bogachev, V. G. Nikiforov, A. D. Voloshina, R. R. Zairov, A. R. Mustafina, A. S. Mereshchenko, B. S. Akhmadeev, “Dual contrasting ability of NaGd0.7Eu0.3F4 nanocrystals tuned by their hydrophilic coating mode”, Mendeleev Commun., 2024, том 34, выпуск 5,страницы 637

Dual contrasting ability of NaGd0.7Eu0.3F4 nanocrystals tuned by their hydrophilic coating mode

A. P. Dovzhenko^a, A. A. Betina^b, T. S. Bulatova^b, N. A. Bogachev^b, V. G. Nikiforov^c, A. D. Voloshina^a, R. R. Zairov^ad, A. R. Mustafina^a, A. S. Mereshchenko^b, B. S. Akhmadeev^ad

^a A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
^b Institute of Chemistry, St. Petersburg State University, St. Petersburg, Russian Federation
^c E.K. Zavoisky Physical-Technical Institute, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russian Federation
^d Alexander Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russian Federation

Аннотация: This work introduces non-covalent hydrophilic coating of NaGd0.7Eu0.3F4 nanocrystals by polylysine (PL) and polyethyleneimine (PEI) for MRI and fluorescent imaging purposes. PL- and PEI-stabilized nanocrystals exhibit high colloidal stability, cell internalization, fluorescent contrasting of nuclei and cytoplasm, low cytotoxicity, and relaxivity (r1 = 0.17 dm3 mmol−1 s−1 and r1 = 0.23 dm3 mmol−1 s−1).

Ключевые слова: contrast agent, hydrophilic coating, fluoride nanoparticle, cell internalization, fluorescent imaging, polymer, Eu-based luminescence.

Язык публикации: английский

DOI: 10.1016/j.mencom.2024.09.004