O. B. Kazakova, N. I. Medvedeva, G. A. Tolstikov, O. S. Kukovinets, E. Yu. Yamansarov, L. V. Spirikhin, A. T. Gubaidullin, “Synthesis of terminal acetylenes using POCl3 in pyridine as applied to natural triterpenoids”, Mendeleev Commun., 20:4 (2010), 234

Эта публикация цитируется в 17 статьях

Synthesis of terminal acetylenes using POCl₃ in pyridine as applied to natural triterpenoids

O. B. Kazakova^a, N. I. Medvedeva^a, G. A. Tolstikov^a, O. S. Kukovinets^a, E. Yu. Yamansarov^a, L. V. Spirikhin^a, A. T. Gubaidullin^b

^a Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
^b A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation

Аннотация: Four new triterpenoids with alkyne moieties have been synthesized by the proposed procedure; among them, 3β,28-dihydroxy-29-norlup-20(30)-yne has demonstrated antiviral activity against papilloma virus and HCV replicon.

Ключевые слова: natural products, synthesis, triterpenoids, betulin, acetylene compounds.

Язык публикации: английский

DOI: 10.1016/j.mencom.2010.06.018