E. B. Rakhimova, V. Yu. Kirsanov, U. Sh. Kuzmina, I. V. Galyautdinov, Yu. V. Vakhitova, “Synthesis and cytotoxic activity of new hexaazadibenzotetracenes derived from trans-1,2-diaminocyclohexane”, Mendeleev Commun., 33:1 (2023), 112

Эта публикация цитируется в 4 статьях

Communications

Synthesis and cytotoxic activity of new hexaazadibenzotetracenes derived from trans-1,2-diaminocyclohexane

E. B. Rakhimova^a, V. Yu. Kirsanov^a, U. Sh. Kuzmina^b, I. V. Galyautdinov^b, Yu. V. Vakhitova^b

^a Institute of Petrochemistry and Catalysis, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
^b Institute of Biochemistry and Genetics, Ufa Federal Research Center of the Russian Academy of Sciences, Ufa, Russian Federation

Аннотация: A one-pot synthesis of N,N'-disubstituted (3bR*,7aR*,10bR*,14aR*)-octadecahydro-1H ,8H-2,3a,7b,9,10a,14b-hexaazadibenzo[fg, op]tetracenes via the catalytic heterocyclization of trans-1,6,7,12-tetraaza-perhydrotetracene with formaldehyde or CH₂(NMe₂)₂ and anilines has been accomplished. Preliminary screening of thus obtained perhydro hexaazadibenzotetracenes for cytotoxic activity has been performed.

Ключевые слова: catalysis, heterocyclization, trans-1,2-diaminocyclohexane, anilines, polycyclic compounds, hexaazadibenzotetracenes, cytotoxic activity.

Язык публикации: английский

DOI: 10.1016/j.mencom.2023.01.035

	*Дополнительные материалы:*
		Supplementary_data_1.pdf	2.0 Mb